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AM-2201 is a recreational designer drug that acts as a potent but nonselective full agonist for the cannabinoid receptor.

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AM-2201 is a recreational designer drug that acts as a potent but nonselective full agonist for the cannabinoid receptor.

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AM-2201 is a full agonist for cannabinoid receptors. Affinities are: with a K_i of 1.0 nM at CB₁ and 2.6 nM at CB₂The 4-methyl functional analog MAM-2201 probably has similar affinities.^] AM-2201 has an EC₅₀ of 38 nM for human CB₁ receptors, and 58 nM for human CB₂ receptorsAM-2201 produces bradycardia and hypothermia in rats at doses of 0.3-3 mg/kg, comparable to the potency of JWH-018 in rats, suggesting potent cannabinoid-like activity.

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